According to Dr. Norman Shealy, magnesium and taurine are essential nutrients that are sorely lacking in depression and anxiety patients and in the general population. He gives more info on his site about which forms of magnesium are better assimilated. He came to my attention when I heard his interview on a podcast called "Theatre of the Mind" -it's free on itunes- subject title "Depression". He also mentions the Liss CES machine and one other device for relaxation as an effective treatment. His site is normshealy.com. He also has a book out on stress relief.